ComboFix
ComboFix is a great tool for removing some spyware infections from your PC.
ComboFix was specifically designed with SurfSideKick, QooLogic, Look2Me, and Vundo in mind.
For other spyware infections you can look at one of the mainstream free spyware removal packages.
ComboFix also has the ability to unhook any Windows System32 .DLL file. This is useful for manually eradicating new spyware applications — including those not yet fixable by the mainstream spyware removal applications.
ComboFix isn’t the be-all end-all tool for fighting spyware, but it is an important and useful tool for any anti-spyware toolbox.